Identification of factors associated with morbidity and postoperative length of stay in surgically managed chronic subdural haematoma using electronic health records: a retrospective cohort study.

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dc.creatorStubbs, Daniel J
dc.creatorDavies, Benjamin M
dc.creatorBashford, Tom
dc.creatorJoannides, Alexis J
dc.creatorHutchinson, Peter J
dc.creatorMenon, David K
dc.creatorErcole, Ari
dc.creatorBurnstein, Rowan M
dc.date2020-05-11T23:32:17Z
dc.date2020-05-11T23:32:17Z
dc.date2020-06-30
dc.date.accessioned2026-08-03T01:55:16Z
dc.descriptionINTRODUCTION: Chronic subdural haematoma (cSDH) tends to occur in older patients, often with significant comorbidity. The incidence and effect of medical complications as well as the impact of intraoperative management strategies are now attracting increasing interest. OBJECTIVES: We used electronic health record data to study the profile of in-hospital morbidity and examine associations between various intraoperative events and postoperative stay. DESIGN, SETTING AND PARTICIPANTS: Single-centre, retrospective cohort of 530 cases of cSDH (2014-2019) surgically evacuated under general anaesthesia at a neurosciences centre in Cambridge, UK. METHODS AND OUTCOME DEFINITION: Complications were defined using a modified Electronic Postoperative Morbidity Score. Association between complications and intraoperative care (time with mean arterial pressure <80 mm Hg, time outside of end-tidal carbon dioxide (ETCO2) range of 3-5 kPa, maintenance anaesthetic, operative time and opioid dose) on postoperative stay was assessed using Cox regression. RESULTS: 53 (10%) patients suffered myocardial injury, while 24 (4.5%) suffered acute renal injury. On postoperative day 3 (D3), 280 (58% of remaining) inpatients suffered at least 1 complication. D7 rate was comparable (57%). Operative time was the only intraoperative event associated with postoperative stay (HR for discharge: 0.97 (95% CI: 0.95 to 0.99)). On multivariable analysis, postoperative complications (0.61 (0.55 to 0.68)), anticoagulation (0.45 (0.37 to 0.54)) and cognitive impairment (0.71 (0.58 to 0.87)) were associated with time to discharge. CONCLUSIONS: There is a high postoperative morbidity burden in this cohort, which was associated with postoperative stay. We found no evidence of an association between intraoperative events and postoperative stay.
dc.descriptionWellcome Trust Studentship
dc.formatElectronic
dc.formatapplication/pdf
dc.identifier2044-6055
dc.identifierhttps://www.repository.cam.ac.uk/handle/1810/305275
dc.identifier10.17863/CAM.52361
dc.identifier2044-6055
dc.identifier.urihttps://repo.dare.co.zw/handle/123456789/161444
dc.languageeng
dc.languageeng
dc.publisherBMJ
dc.publisherhttps://doi.org/10.1136/bmjopen-2020-037385
dc.rightsAll rights reserved
dc.rightshttp://purl.org/NET/rdflicense/allrightsreserved
dc.subjectanaesthetics
dc.subjectepidemiology
dc.subjectneurosurgery
dc.subjectquality in health care
dc.subjectstatistics & research methods
dc.subjectAdult
dc.subjectCohort Studies
dc.subjectElectronic Health Records
dc.subjectFemale
dc.subjectHematoma, Subdural, Chronic
dc.subjectHumans
dc.subjectLength of Stay
dc.subjectMale
dc.subjectMorbidity
dc.subjectPostoperative Complications
dc.subjectRetrospective Studies
dc.subjectSex Factors
dc.titleIdentification of factors associated with morbidity and postoperative length of stay in surgically managed chronic subdural haematoma using electronic health records: a retrospective cohort study.
dc.typeArticle

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