Single-bite versus double-bite technique for mapping biopsies during endoscopic surveillance for hereditary diffuse gastric cancer: a single-centre, randomized trial

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Thieme
https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1201-3125

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Abstract Background and Aims Endoscopic surveillance is recommended in patients with Hereditary Diffuse Gastric Cancer (HDGC) that want to delay or refuse surgery. Since early signet ring cell carcinoma (SRCC) can be inconspicuous, current surveillance endoscopy protocol entails 30 random biopsies which are time-consuming. This study aimed to compare single and double-bite techniques in HDGC surveillance.
The study has received infrastructure support from the Experimental Cancer Medicine Center and Cambridge Biomedical Research Center. AP was funded by a CRUK Multidisciplinary Project Award (C47594/A21202).

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