WHO consolidated guidelines on tuberculosis: module 3: diagnosis – rapid diagnostics for tuberculosis detection: web annex 2. GRADE profiles

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dc.coverageGeneva
dc.creatorWorld Health Organization
dc.date2020-09-04T12:25:34Z
dc.date2020-09-04T12:25:34Z
dc.date2020-09-04
dc.date.accessioned2026-08-03T14:56:56Z
dc.descriptioniv, 66 p.
dc.descriptionThis web annex forms part of the WHO consolidated guidelines on tuberculosis. Module 3: diagnosis – rapid diagnostics for tuberculosis detection and presents the GRADE (Grading of Recommendations Assessment, Development and Evaluation) evidence profiles that informed the guideline recommendations. It compiles structured assessments of the certainty of evidence and the balance of benefits and harms for rapid diagnostic technologies used to detect tuberculosis and drug resistance, including molecular assays, first-line and second-line line probe assays (FL-LPA and SL-LPA), and the lateral flow urine lipoarabinomannan (LF-LAM) assay. The annex summarizes evidence across a wide range of clinical questions and patient populations, including adults and children with pulmonary tuberculosis, extrapulmonary tuberculosis and HIV-associated disease. For each PICO question, it provides GRADE profiles describing study characteristics, risk of bias, inconsistency, indirectness, imprecision, effect estimates, certainty ratings and references supporting the evidence synthesis. Published in accordance with the WHO handbook for guideline development, the document enhances the transparency of the guideline development process by making the evidence appraisal underpinning WHO recommendations publicly available.
dc.formatapplication/pdf
dc.identifier9789240010246 (electronic version)
dc.identifierhttps://iris.who.int/handle/10665/334148
dc.identifier.urihttps://repo.dare.co.zw/handle/123456789/270697
dc.languageEnglish
dc.languageen
dc.publisherWorld Health Organization
dc.relationRelated document (main document):
dc.relationhttps://iris.who.int/handle/10665/332862
dc.rightsCC BY-NC-SA 3.0 IGO
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/3.0/igo
dc.rightsWorld Health Organization
dc.subjectTuberculosis, Multidrug-Resistant
dc.subjectPreventive Health Services
dc.subjectHealth Planning
dc.subjectGuidelines as Topic
dc.subjectprevention and control
dc.titleWHO consolidated guidelines on tuberculosis: module 3: diagnosis – rapid diagnostics for tuberculosis detection: web annex 2. GRADE profiles
dc.typePublications

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