The battle within: How pathogen effectors suppress NLR-mediated immunity.

Simple item page
dc.creatorWu, Chih-Hang
dc.creatorDerevnina, Lida
dc.date2024-08-13T10:23:22Z
dc.date2023-08
dc.date.accessioned2026-08-03T01:51:21Z
dc.descriptionTo successfully colonise plants, pathogens must circumvent the plant immune system. Intracellular immune receptors of the nucleotide-binding leucine-rich repeat (NLR) class of proteins are major components of the plant immune system. NLRs function as disease resistance genes by recognising effectors secreted by diverse pathogens, triggering a localised form of programmed cell death known as the hypersensitive response. To evade detection, effectors have evolved to suppress NLR-mediated immunity by targeting NLRs either directly or indirectly. Here, we compile the latest discoveries related to NLR-suppressing effectors and categorise these effectors based on their mode of action. We discuss the diverse strategies pathogens use to perturb NLR-mediated immunity, and how we can use our understanding of effector activity to help guide new approaches for disease resistance breeding.
dc.formatPrint-Electronic
dc.formatapplication/pdf
dc.identifier1369-5266
dc.identifierhttps://www.repository.cam.ac.uk/handle/1810/372419
dc.identifier1879-0356
dc.identifier.urihttps://repo.dare.co.zw/handle/123456789/160551
dc.languageeng
dc.publisherElsevier
dc.publisherDepartment of Plant Sciences
dc.publisherhttps://doi.org/10.1016/j.pbi.2023.102396
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectDisease Resistance
dc.subjectPlant Breeding
dc.subjectPlants
dc.subjectPlant Immunity
dc.subjectPlant Diseases
dc.subjectPlant Proteins
dc.titleThe battle within: How pathogen effectors suppress NLR-mediated immunity.
dc.typeArticle

Files

Collections

University of Cambridge Apollo