Lesional skin vascular endothelial growth factor levels correlate with clinical severity in patients with cement allergic contact dermatitis

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dc.creatorZedan, H.
dc.creatorAbdel Baset, H.A.
dc.creatorAbdel Sayed, A.A.
dc.creatorEl Karn, M.F.
dc.creatorMadkor, H.R.H.
dc.date2014-06-17T09:10:07Z
dc.date2014-06-17T09:10:07Z
dc.date2010-12-31
dc.date.accessioned2026-08-03T15:42:02Z
dc.description420-424
dc.descriptionAllergic contact dermatitis to cement is a delayed-type hypersensitivity reaction in which cytokines interferon-gamma [IFN-gamma] and vascular endothelial growth factor [VEGF] may be involved in persisting erythema and oedema. VEGF and IFN-gamma levels in serum and skin lesions were measured in 32 Egyptian building workers with chronic allergic contact dermatitis due to occupational exposure to cement and 20 healthy controls. Dermatitis patients had significantly higher levels of serum and lesional skin VEGF and IFN-gamma than controls. A significant positive correlation was found between tissue VEGF and the eczema area and severity index [EASI] score in dermatitis patients [r = 0.86]. VEGF and IFN-gamma may play a role in the pathogenesis of cement allergic contact dermatitis
dc.formatapplication/pdf
dc.identifier1020-3397
dc.identifierhttp://applications.emro.who.int/emhj/V16/04/16_4_2010_0420_0424.pdf
dc.identifierhttps://iris.who.int/handle/10665/117888
dc.identifier.urihttps://repo.dare.co.zw/handle/123456789/275294
dc.languageEnglish
dc.languageen
dc.relationEMHJ - Eastern Mediterranean Health Journal, 16 (4), 420-424, 2010
dc.subjectDermatitis, Contact
dc.subjectDermatitis, Allergic Contact
dc.subjectVascular Endothelial Growth Factor A
dc.subjectSeverity of Illness Index
dc.subjectDermatitis, Contact
dc.titleLesional skin vascular endothelial growth factor levels correlate with clinical severity in patients with cement allergic contact dermatitis

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