Identification of the viral molecules recognised by influenza specific human cytoxic T lymphocytes.

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dc.creatorSmith, GL
dc.creatorGotch, FM
dc.creatorMcMichael, AJ
dc.creatorMoss, B
dc.date2017-08-02T12:41:06Z
dc.date2017-08-02T12:41:06Z
dc.date1987-02-01
dc.date.accessioned2026-08-03T03:49:46Z
dc.descriptionHuman cytotoxic T cells specific for influenza A virus were tested for recognition of each of the ten influenza A virus proteins expressed in target cells using recombinant vaccinia viruses. They recognized the matrix M1, polymerase PB2, and nucleoproteins of influenza virus in association with MHC class I antigens. These internal viral proteins were seen by CTL in conjunction with one or more of the available dependent HLA gene products. There was no detectable recognition of influenza virus surface glycoproteins in target cells.
dc.formatapplication/pdf
dc.identifier0022-1007
dc.identifierhttps://www.repository.cam.ac.uk/handle/1810/265850
dc.identifier10.17863/CAM.11877
dc.identifier1540-9538
dc.identifier.urihttps://repo.dare.co.zw/handle/123456789/181327
dc.languageeng
dc.publisherRockefeller University Press
dc.publisherhttps://doi.org/10.1084/jem.165.2.408
dc.subjectAntigens, Viral
dc.subjectCell Transformation, Viral
dc.subjectHLA Antigens
dc.subjectHerpesvirus 4, Human
dc.subjectHumans
dc.subjectInfluenza A virus
dc.subjectLymphocytes
dc.subjectRecombination, Genetic
dc.subjectT-Lymphocytes, Cytotoxic
dc.subjectViral Proteins
dc.titleIdentification of the viral molecules recognised by influenza specific human cytoxic T lymphocytes.
dc.typeArticle

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