Molecular Subclusters of Follicular Lymphoma: a report from the UK’s Haematological Malignancy Research Network
Loading...
Date
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
American Society of Hematology
Department of Haematology
https://doi.org/10.1182/bloodadvances.2021005284
Department of Haematology
https://doi.org/10.1182/bloodadvances.2021005284
Abstract
Description
Follicular lymphoma displays morphological and clinical heterogeneity, underpinned by shared molecular pathogenesis. Mutations in epigenetic regulators alongside t(14;18) have been identified as disease initiating events. Additional mutational diversity suggests disease heterogeneity. Whether this resolves into mechanistically distinct subsets remains an open question.